In addition, some studies have suggested that radiation treatment to the pelvis may increase the risk of developing bladder tumors. The Food and Drug Administration has associated pioglitazone with an increased risk of bladder cancer. Bladder Cancer Signs and Symptoms. Types of Bladder Cancer. Bladder Cancer Diagnosis. Bladder Cancer Treatment. Living Beyond Bladder Cancer. Bladder Cancer Clinical Trials and Research. Bladder Cancer Doctors, Surgeons, and Experts.
Learn more about the risk factors for bladder cancer. Smoking Tobacco use is the biggest risk factor for developing bladder cancer. Chemical Exposure Frequent exposure to chemicals that are commonly used in certain jobs may increase bladder cancer risk.
Chronic bladder infections and irritation: Problems associated with increased bladder cancer risks include urinary infections, kidney and bladder stones, and other causes of bladder irritation. Schistosomiasis, a parasitic infection, may reach the bladder and is associated with an increased risk of squamous cell bladder cancer. In the United States, schistosomiasis is very rare. In Africa and the Middle East, where this parasite is more common, squamous cell bladder cancer is more common.
Personal history of bladder cancer: Cancer can occur in other regions of the urothelium, such as in the lining of the kidneys, ureter and urethra. Cancer in any of these areas may increase the risk of another tumor in this layer of cells. People who have bladder cancer need to be closely monitored following treatment because additional tumors in the urothelium are so common. Bladder defects from birth: Normally, the connection between the belly button and the bladder that forms before we are born disappears before birth.
Sometimes, part of this connection remains after birth, and may become cancerous. In another birth defect, the bladder and abdominal wall become fused together, leaving the inner lining of the bladder exposed to other areas of the body.
Even following corrective surgery , people who have or had this condition are at a higher risk for bladder cancer. Chemotherapy and radiation therapy : Long-term use of the chemotherapy drug cyclophosphamide is associated with an increased risk of bladder cancer.
Drinking extra fluids while taking this drug can help lower this risk. Radiation aimed at the pelvis is also considered a risk factor for bladder cancer. Next topic: What are the symptoms of bladder cancer? Make a difference in the fight against cancer by donating to cancer research. Call us anytime. It may be helpful for people who cannot have surgery.
Find out more about radiation therapy here. Bladder cancer has a high risk of recurrence. Doctors usually recommend regular monitoring after treatment. Bladder cancer does not always resolve. Instead, it can become a chronic condition. Regular treatment will be necessary to control the cancer. In the early stages, common symptoms include :. Blood in the urine: This is common.
It can range from being detectable through a microscope to altering the color of the urine completely. Urination habits: A person may need to urinate more often than usual. The symptoms of bladder cancer can resemble those of a bladder infection. It is important to seek medical advice if symptoms persist. The cause of bladder cancer remains unknown , but genetic mutations may play a role.
Smoking tobacco and having exposure to chemicals may cause mutations that lead to bladder cancer. However, these may affect people in different ways. Scientists do not consider genetics to be a major cause of bladder cancer. They do suggest, however, that these factors might make a person more susceptible to the effects of tobacco and certain industrial chemicals. Scientists have identified certain risk factors for bladder cancer, of which smoking is the most important.
People who smoke are at least three times more likely to develop bladder cancer than people who do not smoke. The risk of bladder cancer also increases with age. The average age of diagnosis is Other risk factors may include :. Some medications and dietary supplements, such as pioglitazone Actos and aristolochic acid, may also increase the risk.
According to the University of Oxford in the United Kingdom, a toxin in these plants may have links to kidney problems and cancer in the long term. A doctor will ask about symptoms and medical history. Urothelial cancer can happen in the kidneys and ureters, too, but it's much more common in the bladder.
Most bladder cancers are diagnosed at an early stage, when the cancer is highly treatable. But even early-stage bladder cancers can come back after successful treatment.
For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for bladder cancer that recurs. If you notice that you have discolored urine and are concerned it may contain blood, make an appointment with your doctor to get it checked. Also make an appointment with your doctor if you have other signs or symptoms that worry you. Bladder cancer develops when cells in the bladder begin to grow abnormally, forming a tumor in the bladder.
Bladder cancer begins when cells in the bladder develop changes mutations in their DNA. A cell's DNA contains instructions that tell the cell what to do.
The changes tell the cell to multiply rapidly and to go on living when healthy cells would die. The abnormal cells form a tumor that can invade and destroy normal body tissue. In time, the abnormal cells can break away and spread metastasize through the body. Different types of cells in your bladder can become cancerous.
The type of bladder cell where cancer begins determines the type of bladder cancer.
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